Trending...
- Governor Newsom honors fallen California Highway Patrol Officer Miguel Cano
- Governor Newsom marks historic expansion of California's Film and Television Tax Credit Program, announces 16 new projects to film in the Golden State
- California: Governor Newsom announces appointments 7.2.25
PM20D1 Activity Assay Kit is a simple, rapid and sensitive assay to detect the activity of PM20D1 in various sample types.
MILPITAS, Calif. - Californer -- Peptidase M20 domain containing 1 (PM20D1), also known as N-fatty-acyl-amino acid synthase/hydrolase, is a secreted enzyme that catalyzes the biosynthesis of N-fatty acyl amino acids (NAAs) from free amino acids and free fatty acids and also catalyzes the reverse hydrolysis reaction. NAAs play an important role in various physiological functions as lipid signaling molecules.
Additionally, they can stimulate oxidative metabolism via mitochondrial uncoupling. Mouse and human PM20D1 share about 71% amino acid identity. PM20D1 is involved in energy homeostasis. Ablation of PM20D1 in mice has shown bidirectional dysregulation of circulating NAAs, insulin resistance, altered body temperature, glucose intolerance etc. PM20D1 has also been associated with Alzheimer's disease. Therefore, studying PM20D1 activity is of great interest in treating obesity, obesity-related disorders and neurological diseases.
More on The Californer
BioVision's PM20D1 Activity Assay Kit is a simple, rapid and sensitive assay to detect the activity of PM20D1 in various sample types. In this assay, PM20D1 catalyzes the conversion of N-Oleoyl-Glycine to generate glycine. In the subsequent steps, glycine in the presence of converter and developer generate hydrogen peroxide, which reacts with the PM20D1 probe to generate color measured at OD 570 nm. The assay can detect less than 0.1 mU under the assay conditions.
Figures. (A) Glycine Standard Curve. (B) PM20D1 reaction kinetics in rat liver lysate (54 µg), rat kidney lysate (30 µg), and PM20D1 Positive Control. (C) PM20D1 activity in rat liver lysate (54 µg), rat kidney lysate (30 µg) samples. Assay was performed following the kit protocol.
Storage Conditions -20 °C
USAGE For Research Use Only! Not For Use in Humans.
For more information on this Assay Kit Cat# K2107 https://bit.ly/3tDY2ZE
Additionally, they can stimulate oxidative metabolism via mitochondrial uncoupling. Mouse and human PM20D1 share about 71% amino acid identity. PM20D1 is involved in energy homeostasis. Ablation of PM20D1 in mice has shown bidirectional dysregulation of circulating NAAs, insulin resistance, altered body temperature, glucose intolerance etc. PM20D1 has also been associated with Alzheimer's disease. Therefore, studying PM20D1 activity is of great interest in treating obesity, obesity-related disorders and neurological diseases.
More on The Californer
- Utah Metal Fabricator Titan Forge Builds Momentum with Custom Steel Projects and Spiral Staircases
- Jason Koch: Pioneering the Future of Real Estate Development in New Jersey
- Amid Trump's assault on public lands, California conserves over one million acres of land and coastal waters in just one year
- California: Governor Newsom announces appointments 7.7.25
- City of Long Beach to Upgrade Its Internet Infrastructure to Enhance City Network Reliability and Performance
BioVision's PM20D1 Activity Assay Kit is a simple, rapid and sensitive assay to detect the activity of PM20D1 in various sample types. In this assay, PM20D1 catalyzes the conversion of N-Oleoyl-Glycine to generate glycine. In the subsequent steps, glycine in the presence of converter and developer generate hydrogen peroxide, which reacts with the PM20D1 probe to generate color measured at OD 570 nm. The assay can detect less than 0.1 mU under the assay conditions.
Figures. (A) Glycine Standard Curve. (B) PM20D1 reaction kinetics in rat liver lysate (54 µg), rat kidney lysate (30 µg), and PM20D1 Positive Control. (C) PM20D1 activity in rat liver lysate (54 µg), rat kidney lysate (30 µg) samples. Assay was performed following the kit protocol.
Storage Conditions -20 °C
USAGE For Research Use Only! Not For Use in Humans.
For more information on this Assay Kit Cat# K2107 https://bit.ly/3tDY2ZE
Source: BioVision Inc
0 Comments
Latest on The Californer
- Bach and Beyond: Cellists Return to the Beach for 2nd Annual Bethany Beach Cellofest
- Boleros de Noche presents "Marisoul y Los Hermanos Carlos" & "Bolero Soul" at The Ford
- Krispy Kreme, Inc. (DNUT) Investors Who Lost Money Have Opportunity to Lead Securities Fraud Lawsuit
- The 17th Annual Hola Mexico Film Festival presented by Toyota September 12-20 during Hispanic Heritage Month Official Poster Reveal
- NR7 Miner launches zero-cost USDT cloud mining service: daily stable income + referral rewards for double profit
- "The Grateful Dead — 60 Years in San Francisco" - Pantheon Media Launches New Podcast Series and Interactive "Hit Replay" App
- Deaths Spur Closures, but Troubled Teen Camps Must Be Banned, CCHR Warns
- Kiavi Expands Leadership Team to Further Bolster Construction Lending Growth
- Palmer Lake Wine Festival To Build Bridges in Small Mountain Community, Highlight Local Businesses
- Swim Up Hill Appoints Ambassador Lawson, Rep. Towns, and Banker Henderson to Board of Directors
- Paralympic Medalist Jamal Hill Launches Official Road to LA28 Campaign and $3M Corporate Fundraising Initiative
- AI-powered Virtual Staining of Biopsies for Transplant Diagnostics
- Jamal Hill, Duke of LA28 and ESPY Nominee, to Attend 2025 ESPYs and Host Exclusive LA28 Cocktail Party at Yamashiro Hollywood
- Swim Up Hill Games Launches Beta Version of Runner-Style Swim Game to Advance Global Water Safety
- Swim Up Hill, California Science Center Launch First Virtual Swim Experience in LA84-Funded Exhibit
- California: TOMORROW: Governor Newsom to join federal, state, and local leaders to recognize six-month anniversary of Los Angeles firestorms
- Skool Alternatives Reddit: Skool vs Circle vs Whop - Did you join one yet?
- Southern Soul Artist Moe Z Releases New Single 'Set It Out' Distributed by Morris Day Entertainment
- SacraPod Suites Unveils AI-Powered 'Work + Rest' Smart Hospitality Model for Retrofitting Underused Motels Across the U.S
- Green Jacket Gateway" System: Your Definitive Path to Golfing Greatness