Trending...
- Governor Newsom honors fallen California Highway Patrol Officer Miguel Cano
- Spartan & Guardians Partner with Guitar Legend Buckethead to Support Global Child Rescue Efforts
- Plan to Launch Silo Technologies' Cybersecurity Pilot Program for Ultimate Nationwide Deployment via Exclusive Partnership: Stock Symbol: BULT
LOS ANGELES - Californer -- Histological staining has been routinely carried out in pathology laboratories to assist in assessing pathophysiology and disease diagnostics. Despite its widespread use, standard histological staining procedures are plagued with drawbacks such as labor-intensive preparation, lengthy turnaround time, high costs, and inconsistent outcomes.
Virtual staining, a deep learning-based method to digitally generate histological stains, has the potential to revolutionize traditional histological staining workflows. By eliminating the need for chemical staining and toxic compounds, virtual staining provides a rapid, cost-effective, and accurate alternative to traditional staining methods, which can potentially improve the accuracy and speed of diagnoses, leading to better patient outcomes and reduced healthcare costs.
The Ozcan group at UCLA has recently published a Review paper on this emerging virtual staining technology. Titled "Deep Learning-enabled Virtual Histological Staining of Biological Samples," this Review paper provides a comprehensive overview of recent advances in the virtual staining field. It covers the basic concepts, the typical development workflow, key results and progress, and the future perspectives of deep learning-enabled virtual staining technology.
More on The Californer
Published in Light: Science & Applications, a journal of the Springer Nature, this paper provides a valuable resource for scholars, optical engineers, microscopists, computer scientists, biologists, histologists, and pathologists alike. "We believe this Review paper will serve as an atlas of the technical developments in this research area, providing a top-level understanding of the latest advancements in virtual staining," said Dr. Aydogan Ozcan, "and we hope it will inspire readers from diverse scientific fields to further expand the scope and applications of this exciting field and continue to push the boundaries of what is possible with virtual staining".
The Ozcan group is a research group based at the University of California, Los Angeles, dedicated to developing innovative optical imaging and analysis tools for various applications, including biomedicine, diagnostics, and environmental monitoring. The group is committed to advancing virtual staining technology and bringing this cutting-edge technology to the field of digital pathology using deep learning. The research was led by Dr. Aydogan Ozcan, Chancellor's Professor and Volgenau Chair for Engineering Innovation at UCLA and HHMI Professor with the Howard Hughes Medical Institute. The other authors of this work include Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, and Nir Pillar, all from the Electrical and Computer Engineering department at UCLA. Prof. Ozcan also has UCLA faculty appointments in the bioengineering and surgery departments and is an associate director of the California NanoSystems Institute. He co-founded Pictor Labs, a company commercializing virtual staining technology.
More on The Californer
This work was supported by the US National Science Foundation (NSF).
Original article: Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, Nir Pillar, and Aydogan Ozcan "Deep Learning-enabled Virtual Histological Staining of Biological Samples", Light: Science & Applications (2023) https://www.nature.com/articles/s41377-023-01104-7
Virtual staining, a deep learning-based method to digitally generate histological stains, has the potential to revolutionize traditional histological staining workflows. By eliminating the need for chemical staining and toxic compounds, virtual staining provides a rapid, cost-effective, and accurate alternative to traditional staining methods, which can potentially improve the accuracy and speed of diagnoses, leading to better patient outcomes and reduced healthcare costs.
The Ozcan group at UCLA has recently published a Review paper on this emerging virtual staining technology. Titled "Deep Learning-enabled Virtual Histological Staining of Biological Samples," this Review paper provides a comprehensive overview of recent advances in the virtual staining field. It covers the basic concepts, the typical development workflow, key results and progress, and the future perspectives of deep learning-enabled virtual staining technology.
More on The Californer
- Luxury Auto Detailing Brings High-End Mobile Car Care to Cherry Valley and Surrounding Areas
- Transgender Visual Artist Debuts New Work
- Stay Cool All Day With BGMgirl Drawstring Half Wigs
- California: Governor Newsom proclaims Independence Day 2025
- Gundam GQuuuuuuX Takes Center Stage at Anime Expo 2025
Published in Light: Science & Applications, a journal of the Springer Nature, this paper provides a valuable resource for scholars, optical engineers, microscopists, computer scientists, biologists, histologists, and pathologists alike. "We believe this Review paper will serve as an atlas of the technical developments in this research area, providing a top-level understanding of the latest advancements in virtual staining," said Dr. Aydogan Ozcan, "and we hope it will inspire readers from diverse scientific fields to further expand the scope and applications of this exciting field and continue to push the boundaries of what is possible with virtual staining".
The Ozcan group is a research group based at the University of California, Los Angeles, dedicated to developing innovative optical imaging and analysis tools for various applications, including biomedicine, diagnostics, and environmental monitoring. The group is committed to advancing virtual staining technology and bringing this cutting-edge technology to the field of digital pathology using deep learning. The research was led by Dr. Aydogan Ozcan, Chancellor's Professor and Volgenau Chair for Engineering Innovation at UCLA and HHMI Professor with the Howard Hughes Medical Institute. The other authors of this work include Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, and Nir Pillar, all from the Electrical and Computer Engineering department at UCLA. Prof. Ozcan also has UCLA faculty appointments in the bioengineering and surgery departments and is an associate director of the California NanoSystems Institute. He co-founded Pictor Labs, a company commercializing virtual staining technology.
More on The Californer
- John Duffy Competes in Mr Muscle Beach
- New Release: 'The Invisible Alternative' Unveiled by Atrisk Corporation, Resilient
- Thorn & Bloom Magazine Unveils Groundbreaking Second Edition: "Breaking the Cycle"
- Cheap O SMS Launches Groundbreaking Free SMS API Service
- California: Governor Newsom signs legislation 7.3.25
This work was supported by the US National Science Foundation (NSF).
Original article: Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, Nir Pillar, and Aydogan Ozcan "Deep Learning-enabled Virtual Histological Staining of Biological Samples", Light: Science & Applications (2023) https://www.nature.com/articles/s41377-023-01104-7
Source: UCLA ITA
Filed Under: Science
0 Comments
Latest on The Californer
- Countrywide Fence Rental Expands its Temporary Fence Rental Business in Minnesota Area
- A Shepherd's Legacy: Honoring the Life and Impact of Pastor Ross Reinman
- California: Here's how President Trump's tax cuts for the ultra-rich will hurt YOU
- New Media Film Festival Announces Winners
- New Podcast "Spreading the Good BUZZ" Hosted by Josh and Heidi Case Launches July 7th with Explosive Global Reach and a Mission to Transform Lives
- DetailAxis Unveils it's 'Business Engine': Powerful AI Systems for Auto Appearance Pros
- California: Governor Newsom announces appointments 7.2.25
- The Herbal Care, Led by Markel Bababekov, Becomes a Top Dispensary in NYC's Upper East Side
- Digital Watchdog Launches New myDW Cloud Services
- Governor Newsom honors fallen California Highway Patrol Officer Miguel Cano
- Stan Fitzgerald Appointed Acting Press Secretary for Veterans for America First VFAF Georgia State Chapter
- Drone Light Shows Emerge as the New Standard in Live Event Entertainment
- Lore Link is Here to Help Organize Your Game
- Governor Newsom marks historic expansion of California's Film and Television Tax Credit Program, announces 16 new projects to film in the Golden State
- Talar Guedikian Named Winner of 2025 AAJ Paralegal of the Year Award, Sponsored by Advocate Capital
- Chappaqua's Annual Townwide Summer Sale – Unbeatable Savings at Your Favorite Local Boutiques!
- Skyline Partners with ZenSpace to Offer Private Meeting Pods for Trade Show Exhibitors
- California: Did gas prices go up by 65 cents at the pump? No.
- Snell & Wilmer Welcomes Associate Victoria Cendejas to the Orange County Office
- Crime in California drops again — state records second-lowest homicide rate since 1966