Trending...
- California: Governor Newsom announces new tax credits that will generate $2.1 billion investment in world's 4th largest economy
- New PSA Campaign to Address Black Maternal and Infant Mortality in Los Angeles County
- EY US unveils Lance Watkins of Tenant Inc. as an Entrepreneur Of The Year® 2025 Pacific Southwest Award finalist
SAN DIEGO - Californer -- Provenance Bio, an alternative protein company, announced today that its hydroxylated type I collagen protein demonstrates proof of function by matching the cell adhesion strength of fibronectin, providing promising scalable and sustainable protein solutions across various sectors, including pharmaceuticals.
Microbial-based systems for protein production can make proteins at large manufacturing scales, however, functional animal proteins which undergo post translational modifications (PTMs), remain challenging to these expression systems. Provenance's proprietary precision fermentation platform represents a major biotechnological achievement by enabling cost-effective, sustainable, and scalable recombinant solutions for high value markets. Moreover, and equally important, Provenance Bio's full-length hydroxylated type I collagen protein demonstrates cell adhesion properties comparable to fibronectin, a principal protein used for cell culturing in research and development and pharmaceutical production.
Key Findings:
More on The Californer
The global market for cell adhesion proteins is rapidly expanding, driven by innovations in cell therapies, cultured meat development, biomaterials, and animal-free products. Provenance Bio's precision fermentation techniques have enabled the production of high-value recombinant collagen and gelatin at scale, positioning the company as a key player in the transition to sustainable protein solutions.
About Provenance Bio's Precision Fermentation Platform
Provenance Bio utilizes a unique compartment within the microbial host cell to produce and modify recombinant animal protein without the use of any animal products. The system enables precise and high-yielding protein expression and post-translational modifications (the addition of certain functional groups to the protein, such as hydroxylation), for the production of bioactive proteins at scale. Additionally, the platform supports product customization to meet specifications such as protein length, bloom strength, and viscosity for a wide range of applications.
About Cell Adhesion Proteins
Cell adhesion proteins, part of the extracellular matrix (ECM), are essential to cell and tissue cultures which are widely used in the life sciences and biomedical research and development. These proteins, e.g. laminin, fibronectin, and collagen are used for coating the cell culture vessels to enhance cell attachment and to stimulate differentiation, migration, structural support and cellular communication, to ultimately mimic the natural behavior of the studied cells. According to Grand View Research Report, the global cell culture protein surface coatings market was valued at USD 826.5 million in 2022 and is expected to expand at a compound annual growth rate (CAGR) of 15.29% from 2023 to 2030. Stem cell therapy and regenerative medicine are two major fields that are driving the industry growth. Animal derived protein sources have dominated the global industry, however ethical and religious views are driving demand for animal-free components.
More on The Californer
About Provenance Bio
Provenance is an alternative protein company pioneering molecular biology tools for sustainable products. The company's proprietary micro-compartmentalization protein expression platform represents the future of biomanufacturing. For further information, visit: https://provenance.bio or email info@provenance.bio
Microbial-based systems for protein production can make proteins at large manufacturing scales, however, functional animal proteins which undergo post translational modifications (PTMs), remain challenging to these expression systems. Provenance's proprietary precision fermentation platform represents a major biotechnological achievement by enabling cost-effective, sustainable, and scalable recombinant solutions for high value markets. Moreover, and equally important, Provenance Bio's full-length hydroxylated type I collagen protein demonstrates cell adhesion properties comparable to fibronectin, a principal protein used for cell culturing in research and development and pharmaceutical production.
Key Findings:
- Provenance Bio's unique expression system produced hydroxylated, functional, and bioidentical collagen proteins
- Provenance's hydroxylated collagen proteins promote cell adhesion at a strength equivalent to traditionally used fibronectin in cultured human fibroblast cells
- Provenance collagen also performs head-to-head with human collagen and fibronectin when coated on tissue culture plates demonstrating similar adherence and dissociation with fibroblast cells
- Provenance Bio's collagen protein is being produced at an efficiency that will be cost competitive with animal proteins
More on The Californer
- Fairmint Introduces First Fully Onchain and Open Cap Table Infrastructure
- Vortex Brands Begins Gold Purchases Under New Joint Venture with Dubai-Based Partner
- Porta Potty USA Expands its Convenient Portable Restroom Rental Services Business in Louisiana Area
- Miss United Crown of America Launches as a National Platform for Purpose-Driven Titleholders
- Judge Joscelyn Jones Honored with Toastmasters Award for Communication and Leadership Excellence
The global market for cell adhesion proteins is rapidly expanding, driven by innovations in cell therapies, cultured meat development, biomaterials, and animal-free products. Provenance Bio's precision fermentation techniques have enabled the production of high-value recombinant collagen and gelatin at scale, positioning the company as a key player in the transition to sustainable protein solutions.
About Provenance Bio's Precision Fermentation Platform
Provenance Bio utilizes a unique compartment within the microbial host cell to produce and modify recombinant animal protein without the use of any animal products. The system enables precise and high-yielding protein expression and post-translational modifications (the addition of certain functional groups to the protein, such as hydroxylation), for the production of bioactive proteins at scale. Additionally, the platform supports product customization to meet specifications such as protein length, bloom strength, and viscosity for a wide range of applications.
About Cell Adhesion Proteins
Cell adhesion proteins, part of the extracellular matrix (ECM), are essential to cell and tissue cultures which are widely used in the life sciences and biomedical research and development. These proteins, e.g. laminin, fibronectin, and collagen are used for coating the cell culture vessels to enhance cell attachment and to stimulate differentiation, migration, structural support and cellular communication, to ultimately mimic the natural behavior of the studied cells. According to Grand View Research Report, the global cell culture protein surface coatings market was valued at USD 826.5 million in 2022 and is expected to expand at a compound annual growth rate (CAGR) of 15.29% from 2023 to 2030. Stem cell therapy and regenerative medicine are two major fields that are driving the industry growth. Animal derived protein sources have dominated the global industry, however ethical and religious views are driving demand for animal-free components.
More on The Californer
- California: Governor Newsom announces appointments 5.8.25
- Long Beach Parks, Recreation and Marine and Fire Department to Host Water Safety Day
- Terra Divine Skincare Earns Coveted Spot on Organically Becca's Clean Brand Master List
- NBA Champion Lamar Odom Launches Anti-Addiction Meme Coin, Ushering in a Disruptive Innovation in Web3
- Emmetra Partners with Renesas to Advance Agentic AI-Powered Imaging Solutions
About Provenance Bio
Provenance is an alternative protein company pioneering molecular biology tools for sustainable products. The company's proprietary micro-compartmentalization protein expression platform represents the future of biomanufacturing. For further information, visit: https://provenance.bio or email info@provenance.bio
Source: Provenance Bio
0 Comments
Latest on The Californer
- Zefr Announces Launch of Pre-Screen Brand Safety Solution for Google's Search Partner Network (SPN)
- Pathways to Adulthood Conference May 17 at Melville Marriott Honoring NYS Assembly Member Jodi Giglio, Suffolk County Legislator Nick Caracappa
- Adster Techologies awarded US Patent for breakthrough innovation in reducing latency in Ad Serving
- Flexi-View Lending Closes $5.05 Million Residential Acquisition Loan in Billings, Montana
- Robert Fabbio Inducted into the Austin Technology Council Hall of Fame
- California: Governor Newsom, Superintendent Thurmond announce over $618 million to support another 458 community schools
- California: Governor Newsom announces judicial appointments 5.7.25
- Long Beach to Commemorate its Naval History with Commemorative Community Event
- Long Beach: City Celebrates Inaugural National Home Improvement Month: Love Where You Live
- California sues Trump administration for illegally withholding billions in bipartisan infrastructure funds: 'Another Trump gift to China'
- Tale of two trains: California high-speed rail leaves Texas in the dust
- California: State invests nearly $33 billion in cap-and-trade dollars to make communities cleaner and healthier
- Where AI Falls Short, Real Connections Rise—Media Outreach with Heart
- Cybersecurity is Protecting Your Personal Information and Your Portfolio
- EY US unveils Puneet Nanda of GuruNanda as an Entrepreneur Of The Year® 2025 Award Finalist
- California: Governor Newsom proclaims Children's Mental Health Awareness Week 2025
- VC Mastermind Launches: A Private Global Network and Podcast for Top-Tier Venture Capital Leaders
- L2 Aviation Celebrates Grand Opening of New Facility at Cincinnati/Northern Kentucky International Airport (CVG)
- Actor and Writer Ernie Rivera Launches Groundbreaking Indie Superhero Thriller, Citadel Lost, with Full Campaign and Industry Buzz
- Managing Summer Staffing Surges with Confidence: Why Name Badges Are a Must for Seasonal Success